Sioux City, Iowa Hotel's Full-Service Makes the Difference When your travels bring you to Sioux City, Iowa, our hotel's friendly staff shows our commitment to hospitality sets us apart. Situated conveniently off of I-29 at exit 147B, the Holiday Inn® Sioux City hotel's location is close to the area's major businesses and attractions. Fun is just around the corner for our hotel's guests in Sioux City, Iowa. From the exhibits at the Lewis & Clark Interpretive Center to great sporting events and live entertainment at Tyson Event Center to the new Sioux City Hard Rock Casino,or a show at the Historic Orpheum Theater, our city offers something enjoyable for everyone. Business travelers love our hotel's downtown Sioux City, Iowa address. We're near Mercy Medical Center, St Luke's Hospital, June E. Nylen Cancer Center, the Sioux City Convention Center, Cargill, Morningside College, Briar Cliff University and Western Iowa Tech Community College are nearby. We provide a Business Center and meeting rooms, too. Our airport shuttle makes travel to Sioux City Airport a snap. No matter what brings you here, our winning combination of amenities which includes our free 24 hour shuttle and service makes you welcome in Sioux City. Our hotel's free high-speed, Wi-Fi Internet access, Fitness Center, indoor pool and full-service restaurant ensure comfort and convenience. We look forward to your visit!