The Hampton Inn St. Louis Southwest, MO hotel is located on the corner of Interstate 44 and Highway 141, at Exit 272 in southwest St. Louis, Missouri. The hotel is near many corporations and attractions such as Six Flags, the Fenton Daimler Chrysler Plant, Maritz Inc. headquarters, TQ3, Unigroup Corporation, Anheuser Busch Soccer Park, Grants Farm, The Magic House, Gravois Bluff shopping complex, and the Fenton Missouri Manufacturing area. Our southwest St. Louis Hampton Inn offers pet friendly and amenity filled hotel rooms that include coffeemaker, hair dryer, refrigerator, microwave, iron and ironing board and complimentary high-speed internet access. Sure to please the busy executive or leisure Missouri traveler, St. Louis Hampton Inn hotel guests will enjoy complimentary On the House hot breakfast buffet served daily. After a busy day, hotel guests can relax in the outdoor pool or work out in the fitness center. We love having you here in Missouri at the Hampton Inn St. Louis Southwest hotel!